As in the “The mysteries you have to conquer if you want to create a new linux_base port” part explained: no, I have not tested any Linux-release, so I do not know if Fedora 15⁄16 will work or not.
As the linux_base port is not a complete Linux userland, and we need only parts of it to have Skype, acroread and other software working, it is still unknown to me if the use of systemd in Fedora 15⁄16 is a showstopper or not.